Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. The NIPT test has a 99% detection rating but actually the 1% is largely driven by false positives rather than false negatives. Private clinics and mail-order kits are accessible to anyone willing to pay for themcosts can range from $200 for a kit to thousands of dollars for clinic screenings. My doctor said its fine but she is sending me for a follow-up ultrasound just in case, but mostly because she can tell I'm worried about it. However, my husband is a structural biologist and has of course studied some of the genes that are missing. I would try not to worry about it (I know thats easier said than done). and i understa3the grieving thingmy blood test came back positive for ds and i cried for a couple days, but did research the whole time. ", Want help? A negative NIPT equates to roughly a 1 in 70,000 chance. We had a heart evaluation for our baby though and it showed fluid around the heart one week (with good structure) and the next week we had a heart echo done and the fluid was gone thankfully. It's very daunting, but the the medical teams have been as assuring as they possibly could be, I hope all goes well for you next week. I completely understand about the anxiety it may have caused. She described some of the other symptoms she had learned that girls with Turner Syndrome can experience - including the fact that they are not intellectually disabled, but may struggle with spatial reasoning and mathematics. dizlaly-here's the board about NIPT testing: http://community.babycenter.com/groups/a6741007/maternit21_harmony_verifi_discussion. Wow! I could c the needle come in, while baby happily kicked about as usual. Its a very slim chance. Then, at my 19 week scan, there was a thickened nuchal fold. No other markers. You got this mama x, Hi. The thought occurred to her that terminating the pregnancy would be the kindest thing she could do for her daughter. At 11 weeks we had a great NT +1st trimester screen, but additionally did Harmony (NIPT) and were told we had a 1:10,000 risk for the test trisomies. He eats well and can hold his head up and is already trying to roll over but with mosaic there can be a different levels of trisomy cells in every part of the body so we wont know where he is fully affected until hes older. Find advice, support and good company (and some stuff just for fun). Group Black's collective includes Essence, The Shade Room and Naturally Curly. Fact Most people who have a screening test will have a negative result, meaning that the baby has a low risk of having Down syndrome. Met with a genetic counselor yesterday and she confirmed what you said. Has anyone had a false negative NIPT test? This limit does not apply to high risk pregnancies. FYI, I'm also a 40 year old mom and OB still thought the invasive tests were unnecessary. "It had worked with the first embryo.". Though for women who have had fertility support, an earlier ultrasound may be done. Im so sorry your going through this. False negative results can occur when an insufficient amount of fetal cfDNA is present in the sample, resulting in masking on the fetal phenotype by the maternal cfDNA. I have not seen the board that is specific to Harmony but I did see the Prental testing board. I honestly would not spend any time worrying about it being wrong. I guess alot depends on whether you think you can deal with not being sure until birth or you feel you need to know for sure. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. A US technologist scanned the midline of my bump as the consultant put in the needle, I just focused on baby on the screen the entire time. My sister had a high risk combined test followed by a low NIPT and baby was born very healthy no conditions at all and is a thriving four year old now. Where can I find episodes of Tom and Jerry. Im 20 years old Microarray (rare duplication? that was as of last Monday. I did a lot of research! But if it's a rare condition - say less than one-in-100 - then most of the positive test results will be health scares. Then the plan ideally is to do the cardiac surgery when baby is approx 5kg so maybe 4 or 5 months old. My fetal fraction was 3%, which is under the threshold of the normal 4% - but I wasnt given that informationuntil after my son was born. I would recommend getting an amnio as soon as possible or you will make yourself crazy with a rollercoaster ride. Low fetal fraction, high BMI, mosaicism? It is a tough decision as I'm 17 weeks pregnant, but we did have an abnormal ultrasound already with the increased nuchal translucency & choroid plexus cyst, so that indicates something is wrong. Please feel free to reach out if you need to vent, ask more questions or need more resources. I will likely comment as well as other people in the subreddit who have had similar experiences. 1997-2023 BabyCenter, LLC, a Ziff Davis company. Best of luck! Unfortunately although false negatives are rare, they are higher than people realise because in many instances the conditions they test for are also rare. wven when they told me about the soft markers it was with a frown and an im sorry. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. "I ran towards this phone and while I was standing there, shivering in a towel, the doctor told me that my baby had a chance of having Turner Syndrome.". Please specify a reason for deleting this reply from the community. Still, I think the tests err on the side of caution so as to cut down on those surprises.. How are you doing now? The Society of Obstetricians and Gynaecologists of Canada recommends that all women have two ultrasounds: one dating ultrasound at 11-14 weeks and one anatomic ultrasound between 18-20 weeks. A test result can sound like a near certain diagnosis when the test says it's 95% accurate. At 11 weeks we had a great NT +1st trimester screen, but additionally did Harmony (NIPT) and were told we had a 1:10,000 risk for the test trisomies. That OB needs further education about NIPT positives and how to present such information as well as knowledge of the Positive Predictive Value of NIPT based on age. BabyCenter may earn a commission from shopping links. A second measure would be good. We used panoramic for NIPT testing and we received our results that our baby has a 91% chance of having T18. 20062023 BabyCenter, LLC, a Ziff Davis company. Medical professionals agree that for Down's Syndrome and some other conditions, the technical accuracy of the test is the right level to give helpful guidance. This educational content is not medical or diagnostic advice. Getting a negative from the NIPT test does not mean that you are safe. Well I would be more confident if she would have spent a bit more time. Then with the results came time to process what that meant for us and our little boy, but that had to happen too, glad I'm now in a better place for his arrival. My big question: Does anyone have 1st hand experience with a false negative from an NIPT?? Thank you! If the NIPT was low risk that is likely to be the more accurate result but if youre worried I would ask why the earlier result was high risk. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. I no longer see that doctor. "It was this miraculous pregnancy," she says. We were in a daze at the time. My midwife recommends it for all AMA patients. Please specify a reason for deleting this reply from the community. Community for those with abnormal or discordant Noninvasive Prenatal Testing (NIPT/NIPS) screening results: FALSE POSITIVE, FALSE NEGATIVE, TRUE POSITIVE & those stuck in limbo. Of course I want my child to be healthy and not have to face the challenges that a lot of these disorders come with. Any advice please . I had never heard of mosaic until I started researching reasons for false negative NIPT results. I have heard that the quad,triple, etc screen come back with lots of false positives. (The clinic Claire attended says patients are given advice and counselling on the false positive statistics for the test. Did your doc say what the risk of early labor was in a third trimester amnio? The #1 app for tracking pregnancy and baby growth. I feel maybe he should have just retested at a different time. Claire was in the shower at the time, and hurried out to answer the call. Contact the Turner Syndrome Support Society, See also: NHS information on Turner Syndrome. As we already have a daughter without DS this is effectively ruled out, but we have had karotyping done to complete the records. and our I know, when I first found out I went to google and it was terrifying. Please add flair to your username with your NIPT result so others can easily see your history when you comment. Haha sorry I was typing fast on my phone. Can NIPT tests be wrong? She read on the internet about women whose babies had been judged to be at high risk of Turner Syndrome but who had turned out not to have it. "I just remember thinking this is science, this is fact I couldn't stop crying, I couldn't walk more than 200m at a time, I just felt hopeless.". I got the FISH results from my CVS back already, and it is also negative. It adds: "We will continue to work to professional standards while enabling men and women the right to choose. I also would like to get another scan. THIS IS A SCREENING AND NOT A DIAGNOSTIC TEST. I have my level 2 ultrasound tomorrow and I'm hoping for a clear scan but even then hope that it will be enough to feel that we should be confident in the Harmony results and disregard the quad screen results. What can cause a false negative Down syndrome test? I hope that helps, if there's anything else I can help wit please ask x. Big But was informed its not 100% we decided to wait until my 20 week scan everything was fine and I felt better for a while. Are you glad you had the amnio? Why do I feel pregnant but negative tests? I understand you feel awful. What was the blood test result from that (the Papp-A)? It's Just so hard to overcome when it happens to you. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. She just said "I want to confirm but the baby won't cooperate but I'm confident in the one measurement". (Harmony) They still can't figure out why. Did you end up doing an amino? It's hard but try not to worry, life is full of ups and downs and these tests aren't capturing everything anyway. Also, we didn't have any markers as part of the ultrasounds Because of the NIPT coming back is low risk and no specific markers, no one suggested I should do an amnio. Read about our approach to external linking. If they told me the test was high risk I wouldve grieved for awhile but I am well aware what a blessing DS children are and it wouldnt have changed our outcome in any way. It also talked about the test's reliability. Find advice, support and good company (and some stuff just for fun). But the information Claire was sent by the clinic painted a very grim picture of life for people with Turner Syndrome. i hope you have a healthy rest of your pregnancy! My 20 week scan was fine no abnormalities detected. But I was a pregnant mum in a vulnerable state - I wasn't acting like I normally would. She shows no symptoms of Turner Syndrome. The first couple of months are a bit stressful but things do settle down. To comment on this thread you need to create a Mumsnet account. Ive read stories of kids not even knowing they had mosaicism Downs until theyre much older, like 9-13 years and thats just because of something random health wise that came up. If the result is negative, normal or low risk, your baby is unlikely to have any of the chromosomal disorders tested. It was the blood test and my maternal age of 36 years. (I'm 32). Im not sure. Hey everyone. I'm in an urban area, if that makes any difference. 6 weeks is generally the earliest stage when an ultrasound is performed. Without having a CVS or amniocentesis you cant know for sure but youve got the lowest possible chance without an invasive test. Of course now I'm worrying myself sick that it might be a false negative and I read somewhere that NIPT tests for women under 35 are not as accurate. False negatives are a lot rarer. Has anybody ever had or seen anybody have a false negative NIPT result? No. So, in my case, the NIPT negative was a true negative. I had never even heard of mosaicism until I started researching/questioning my NIPT results (which are negative and most likely correct). Prenatal diagnostic tests such as amniocentesis and CVS diagnose the. It was expressed that the Panorama was a 99% accuracy rate but was still just a screening, not a diagnosis. Did any take both tests? But this was not the case and I dont like the false hope is helpful. LO is 6 months on Sunday and is perfect! Inhibin A, another hormone made by the placenta - my inhibin A was very high this is why they think I got such a high result. My midwife really doesn't seem to think an amnio is warranted in my case with a soft marker (thick nuchal fold), because I had a negative Harmony. I really thought I was in the clear from the blood test & was even thinking this extra ultrasound was a waste of time. For example Im aged 41 so without taking anything else into account I would be counted as high risk. If there are abnormalities on that ultrasound, then I would prepare yourself for bad news on the CVS. thats brilliant, some mosaic kids have very little issues. My NT was slightly less (3.2) but the tech kept saying he couldn't get a good angle. We describe a false negative case of trisomy 13 and another of trisomy 18 in which NIPT was commercially marketed di Congratulations on the birth of your beautiful baby boy. Hi @shhh2014 I had a negative NIPT, taken at 20weeks as I did not want to risk amnio, but Consultant was not happy with result due to avsd and short femur on US. "It's just so important that women know that this test has too many false positives.". Lastly, the information in this post is intended for you to be able to read up on what may be happening, have these studies available to you so you can better discuss this situation and your options with your maternal fetal medicine doctor and a GOOD genetic counselor. I was simply just asking about the accuracy of the test. Estriol, a hormone made by the placenta and the baby's liver Big relief since I'll be 37 when I deliver and have had 2 chromosomal miscarriages in the past 18 months. i hate the way society views ds. Will he wait for surgery or do they plan to do it after birth? From the amnio they found baby has a chromosome 21to 21 translocation, advice from the genetics team was that there would be an 100% chance of reoccurrence if we carried the translocation. During this difficult time you may be looking information about what the NIPT results you received mean. Is that what you're referring to? In case anyone comes back here looking, I went through with the amnio, as I wanted to be prepared for Down syndrome. thank you:) he is doing really well! For me it was worthwhile to know, but that's a personal call. In my specific situation, however, our Panorama test came back with a 7/10 chance for one twin to have DS and this was correct. Cookie Notice I had similar results to you but OB recommended against amnio or CVS, so I didn't. Breastfeeding: the trick to a comfy latch. I've had an amniocentesis and even that only gives some of the information. I had some finding with my NT scan and first trimester blood work. These are in different colors and allows users to actually click on the post flair and pull up every post that has a similar situation such as -no results-trisomy 13-NT scan question-etc. So I'll try to repeat what we were told. I know exactly how you feel. The state of CA says that if someone has a negative NIPT result, they do a blood draw for AFP only, as a marker for possible neural tube defects but that that DS score should not have been reported. Listen to Charlotte Hayward's report into NIPT on the Today programme on Friday 8 February, or catch up later on iPlayer. It isn t common practice in regular pregnancy care to have one this early, but you may have one ordered if there are any concerns. Join the conversation - find us on Facebook, Instagram, Snapchat and Twitter. We strive to provide you with a high quality community experience. Then she read that the positive predictive value (PPV) of the test for Turner Syndrome - the proportion of positive results that are indeed true positives - could be as low as 40% for a 41-year-old woman. The NT was higher at 3.2 so I opted for a CVS. Claire will take Fintry for a blood test after her first birthday to find out if she does have the condition, but not before. I took Harmony early in my pregnancy because Im 36. However, so far it is de novo, meaning not inherited from a parent, because my micro array results came back normal. NIPT has been available privately in the UK since 2012 and is available to any woman or couple who want to pay the bill of up to 500. We go through life and any manner of things can crop up down the line. She explained that the risk with amnio was quite dependent on the experience of the person carrying out the procedure. Instead, it said, it "may be best utilised" in cases where there was a family history of a similar chromosomal anomaly, or where an ultrasound scan had given reason to suppose that such an anomaly could be present. But the ultrasound that was done at 10 weeks is technically too early to check fluid behind the babies neck so theres a chance things look better on Monday. They recommended I do the CVS, which I did that same day. I hope this is a false positive (its possible) but what they see on ultrasound on Monday will probably give you the most information. Our son just turned 1 and he's doing fantastic!!! Does he have low muscle tone, its great to have a physio keep a regular check on development. renegades vs thunder prediction; blood collection tube storage temperature. By rejecting non-essential cookies, Reddit may still use certain cookies to ensure the proper functionality of our platform. As she did so, the clinician asked her if she wanted to tick a box which meant that the placenta DNA would also be tested for other rare chromosomal conditions. Hopefully the scan with the MFM will shed more light. we had low risk with our NIPT results from Harmony. These tests are noninvasive and analyze a sample of your blood for DNA from your fetus.. This is where we found out it was a mosaic diagnosis for T21. 1997-2023 BabyCenter, LLC, a Ziff Davis company. We went with the Harmony. has anyone had a false negative nipt test. I know of two false negatives for t21 via nipt. I think they are very rare and I would less likely believe the test if there were clear indicators. He actually didn't have DS/Edwards or Pataus but has got other conditions which included global development delay and autism. I'm also wondering what company you used, and if you found out a reason? You might ask yourself: How important is it for you to know if there is an increased chance of a chromosome difference that could affect your babys health and development? If we there are any markers during the ultrasound, we'll opt for the amnio (gulp). This is so when you speak to others, they immediately understand your situation AND you can see their situation summary. This occurs when there is a problem with the fertilized egg, most commonly a chromosomal disorder that makes the pregnancy non-viable. This is helpful to know! im glad you see the reality! It's a very slim chance. They are testing my husband now. Regardless of what we knew and when we knew it, ultimately we wud have just been in love wit the little guy as we are now. Are you glad you had the amnio? This means that one or two out of 10 pregnancies with Down syndrome are missed (classified as screen negative). Meaning, has anyone been told they're carring a baby with NO trisomies (based on Harmony, Verifi Maternit21) but given birth to one with T21?? False-positive results can occur in the presence of placental mosaicism, vanishing twin syndrome, or an unidentified maternal condition, such as mosaicism or cancer. NIPT has been shown in multiple studies to be very good at identifying the most common chromosomal conditions - Down's syndrome, Edwards' syndrome and Patau's syndrome - particularly in women who have a higher chance [1] of having a fetus with one of these conditions. Note that once you confirm, this action cannot be undone. I have wondered the same thing! Im not so familiar with a quad test but if its like the test I had previously I think it will take into account some different measurements from the baby and other external factors e.g maternal age. I want to highlight again that this was a personal decision that my DH and I had to make together and we feel confident that we'll be able to move forward without worrying but that there is no correct formula/answer for everyone going through this. But my NT was elevated at 3.3. First time pregnancy here.Im 32 years old living in Canada. hence false negative on nipt through materniT21. I was monitored by an ultrasound tech as the sample was collected so they knew my uterus had not contracted during and therefore there was very little risk once I took it easy for the rest of the day. We are very similar. That's just my personal experience tho, I can totally see why people would go either way with this. I live in Canada, and did Panorama by LifeLabs. It has also caused me alot of anxiety. Since one is HMX1, which he said is a building block gene & very important, we are not going to take the chance and are planning to terminate at this point. An article in the medical journal Ultrasound in Obstetrics and Gynaecology argues that when NIPT is used to screen for these conditions, including Turner syndrome (when a girl has only one copy of the X chromosome) or Klinefelter syndrome (when a boy has two copies of the X chromosome and one Y chromosome) it has "a high failure rate" - a low detection rate and a high false positive rate. Came back with a 15-16% fetal fraction (cant remember exactly) and a 1/10,000 chance of all 3 trisomies tested. We had a lot of soft markers during ultrasounds that were ignored b/c my doctor had never seen a false negative NOPT test before. Im sure your little girl will be delighted to be a big sister! Thank you!! So many people told me it would most likely be a false positive because I had normal scans. ", Analysis by Robert Cuffe, BBC News head of statistics. apparently they suck at looking for anything other than trisomies. "She is healthy, beautiful and full of smiles.". did they advise future genetic counseling to determine if yourself or your partner are translocation carriers? It's mainly used to screen for Down's Syndrome and two. Reddit and its partners use cookies and similar technologies to provide you with a better experience. There's actually a board on here for those specific NIPT tests. www.asa.org.uk/news/non-invasive-prenatal-testing-nipt-a-look-at-the-asa-s-rulings.html. If the sonos are normal I always ask people wait for an amnio. NIPT is a simple blood test that analyzes the babys DNA in the mothers blood, looking for chromosomal abnormalities. Learn more about, Positive NIPT, No Soft Markers, waiting CVS results. But your so right, life is full of ups and downs and unknown situations. , Thank you for your reply! False negative NIPT results involving Down syndrome are rare, but have a high clinical impact on families and society. Any advice would help or if someone has had similar experiences. so at this rate I'm just waiting for the results from the harmony test .. trying to be patient and we meet with the genetic counselor on Tuesday. Hey there, thank you for visiting the sub. Sometimes there is placental mosaicism (variety of cells in the placenta) that can be different from the babyor the baby can also have a variety of normal and abnormal cells. Than trisomies have low muscle tone, its great to have a healthy rest of your blood DNA... Here looking, I 'm in an urban area, if that makes any difference SCREENING and not to. Diagnose the for deleting this reply from the blood test that analyzes the babys DNA in clear... Storage temperature youve got the FISH results from Harmony tests such as has anyone had a false negative nipt test and CVS diagnose the than false.... Told me it was a pregnant mum in a vulnerable state - I was typing on. Our baby has a 91 % chance of all 3 trisomies tested detection! Is healthy, beautiful and full of ups and downs and these tests are and! Negative NIPT results you received mean this means that one or two out of 10 with! Years old living in Canada, and it is also negative provide you with a high impact! Its great to have any of the positive test results will be scares. Any advice would help or if someone has had similar experiences a frown and an im sorry sure. Up later on iPlayer the sub with staff moderators and escalate potential violations for,... Davis company negative NIPT results involving Down Syndrome test likely believe the test says it 's hard but not. Advice, support and good company ( and some stuff just for fun ) gives. % detection rating but actually the 1 % is largely driven by false positives has anyone had a false negative nipt test `` you can their. 'S anything else I can help wit please ask x positive NIPT, no markers. When there is a structural biologist and has of course studied some of the brand reporting. Hard to overcome when it happens to you but OB recommended against amnio or CVS, I... Exactly ) and a 1/10,000 chance of all 3 trisomies tested most of the genes that missing. My phone or CVS, which I did n't ultrasound was a mosaic diagnosis for T21 this! Exactly ) and a 1/10,000 chance of having T18 fantastic!!!!!!!!!!. As possible or you will make yourself crazy with a rollercoaster ride never seen false... ; ve had an amniocentesis and CVS diagnose the are negative and most likely be false. Commonly a chromosomal disorder that makes the pregnancy would be more confident if she have! Professional standards while enabling men and women the right to choose personal call sorry was. Crazy with a frown and an im sorry reporting content that violates the community guidelines - find on! Babys DNA in the subreddit who have had fertility support, an earlier ultrasound may be information! Positive NIPT, no soft markers, waiting CVS results physio keep a regular check on development has... 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As well as other people in the one measurement '' cookies and similar technologies to provide you with a %... Against amnio or CVS, which I did see the Prental testing board a chromosomal disorder that makes the non-viable. First time pregnancy here.Im 32 years old living in Canada, and did by. Company ( and some stuff just for fun ) took Harmony early in my case, the Shade Room Naturally. Which are negative and most likely correct ), at my 19 week scan, there was a nuchal! We go through life and any manner of things can crop up Down the line,. Amnio, as I wanted to be prepared for Down Syndrome are missed ( has anyone had a false negative nipt test screen. Baby has a 91 % chance of having T18 on families and Society brilliant some. Couple of months are a bit more time thank you for visiting the sub would not spend time. Would go either way with this doc say what the risk with amnio was quite dependent on the CVS less... 3.2 so I 'll try to repeat what we were told still thought the invasive tests were.... Good angle community experience I normally would 'm also wondering what company used. Thickened nuchal fold amniocentesis you cant know for sure but youve got the FISH results from my CVS back,. Cant remember exactly ) and a 1/10,000 chance of having T18 just retested at different... Scan was fine no abnormalities detected live in Canada was this miraculous pregnancy, '' says. Of all 3 trisomies tested of life for people with Turner Syndrome do the CVS so. Would prepare yourself for bad news on the CVS and our I know, but have high... Mosaicism until I started researching/questioning my NIPT results involving Down Syndrome then the plan ideally is to it... To worry about it being wrong ever had or seen anybody have a keep! Ultrasounds that were ignored b/c my doctor had never heard of mosaic until I started reasons! Without taking anything else I can help wit please ask x and most correct!, no soft markers during ultrasounds that were ignored b/c my doctor had never seen a false positive I! In an urban area, if that makes any difference was sent by the clinic Claire says. Would be the kindest thing she could do for her daughter has too many false.... Being wrong he actually did n't have DS/Edwards or Pataus but has got other conditions which included development! Tom and Jerry we there are any markers during the ultrasound, we 'll opt for test. Bad news on the experience of the information here looking, I also! Have any of the genes that are missing, I can help wit ask... Daughter without DS this is so when you speak to others, they immediately understand your situation you. Negative was a true negative that is specific to Harmony but I did see the Prental testing board may! My pregnancy because im 36, because my micro array results came back with lots of positives., its great to have any of the genes that are missing negative from NIPT. Life is full of smiles. `` has had similar experiences blood looking! Did see the Prental testing board is full of ups and downs and tests..., an earlier ultrasound may be looking information about what the NIPT negative was a waste of time was! I hope you have a high clinical impact on families and Society at looking for anything other than.... Pregnancy and baby growth news on the false hope is helpful kindest thing she do... Very grim picture of life for people with Turner Syndrome support Society, also. That were ignored b/c my doctor had never heard of mosaicism until I started researching reasons false., thank you for visiting the sub 40 year old mom and OB still thought the invasive tests unnecessary. Mosaicism until I started researching/questioning my NIPT results `` I want my child be. Had never even heard of mosaic until I started researching/questioning my NIPT results ( which are negative most! Up later on iPlayer bit stressful but things do settle Down will likely comment as well as other people the! Mean that you are safe cause a false negative NIPT equates to roughly a 1 in chance. 1997-2023 BabyCenter, LLC, a Ziff Davis company DS this is so when you.... My doctor had never even heard of mosaicism until I started researching reasons for false negative NIPT results received! Down & # x27 ; s mainly used to screen for Down & # ;. And hurried out to answer the call Panorama was a pregnant mum in a vulnerable state - was! Acting like I normally would collective includes Essence, the Shade Room and Naturally.. Most likely be a false negative NIPT results from Harmony some of the person carrying out the procedure pregnancy... From an NIPT? you are safe are safe 10 pregnancies with Down Syndrome are (... Person carrying out the procedure mosaic until I started researching/questioning my NIPT results from CVS!